Browsing by Author "Farkas, Svetlana"

Now showing 1 - 2 of 2
  • Thumbnail Image
    ItemOpen Access
    Mercury-induced toxicity of rat cortical neurons is mediated through N-Methyl-D-Aspartate receptors
    (BioMed Central Ltd., 2012-09-14) Xu, Fenglian; Farkas, Svetlana; Kortbeek, Simone; Chen, Lina; Zhang, Fangxiong; Zamponi, Gerald W.; Syed, Naweed I.
    Mercury is a well-known neurotoxin implicated in a wide range of neurological or psychiatric disorders including autism spectrum disorders, Alzheimer's disease, Parkinson's disease, epilepsy, depression, mood disorders and tremor. Mercury-induced neuronal degeneration is thought to invoke glutamate-mediated excitotoxicity, however, the underlying mechanisms remain poorly understood. Here, we examine the effects of various mercury concentrations (including pathological levels present in human plasma or cerebrospinal fluid) on cultured, rat cortical neurons.
  • Thumbnail Image
    ItemOpen Access
    The establishment of a model for cigarette smoke exposure in pregnant rats
    (2000) Farkas, Svetlana; Hasan, Shabih, V.