Browsing by Author "Gregson, Daniel B"
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Item Open Access Community-Acquired Serratia Marcescens Spinal Epidural Abscess in a Patient Without Risk Factors: Case Report and Review(2008-01-01) Parkins, Michael D; Gregson, Daniel BSerratia marcescens has rarely been reported as an agent of invasive disease in patients presenting from the community. Furthermore, S marcescens is frequently opportunistic, affecting individuals with serious medical comorbidities including immune suppression and diabetes. A case of a community-acquired S marcescens spontaneous lumbar epidural abscess presenting as cauda equina syndrome is reported in a previously well 36-year-old man with no identifiable risk factors. To the authors’ knowledge, this is the first report of invasive S marcescens causing disease in a patient with no medical comorbidities.Item Open Access Human Granulocytic Anaplasmosis: First Reported Case in Canada(2009-01-01) Parkins, Michael D; Church, Deirdre L; Jiang, Xiu Yan; Gregson, Daniel BHuman granulocytic anaplasmosis (HGA) is a tick-borne rickettsial infection of peripheral blood neutrophils caused by Anaplasma phagocytophilum. While this infection is increasingly recognized as endemic throughout much of the United States, no Canadian cases have been previously described, despite the agent being identified in Canadian ticks. Herein we present a case of HGA acquired in an urban Alberta centre. Canadian physicians must be aware of the possibility of tick-borne rickettsial diseases as etiology of fever in individuals presenting with leukopenia/lymphopenia, thrombocytopenia and elevated transaminases during periods of tick activity. Prompt recognition and treatment are important in minimizing resultant morbidity and mortality.Item Open Access Population-Based Surveillance for Hypermucoviscosity Klebsiella pneumoniae Causing Community-Acquired Bacteremia in Calgary, Alberta(2013-01-01) Peirano, Gisele; Pitout, Johann DD; Laupland, Kevin B; Meatherall, Bonnie; Gregson, Daniel BThe characteristics of hypermucoviscosity isolates among Klebsiella pneumoniae causing community-acquired bacteremia were investigated. The hypermucoviscous phenotype was present in 8.2% of K pneumoniae isolates, and was associated with rmpA and the K2 serotype; liver abscesses were the most common clinical presentation. The present analysis represents the first population-based surveillance study of hypermucoviscosity among K pneumoniae causing bacteremia.Item Open Access Rationale for and protocol of a multi-national population-based bacteremia surveillance collaborative(BioMed Central, 2009-07-22) Laupland, Kevin B.; Schønheyder, Henrik C; Kennedy, Karina J; Lyytikäinen, Outi; Valiquette, Louis; Galbraith, John; Collignon, Peter; Church, Deirdre L; Gregson, Daniel B; Kibsey, Pamela