Browsing by Author "Jasaui, Yamile"

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    Barriers to following imaging guidelines for the treatment and management of patients with low-back pain in primary care: a qualitative assessment guided by the Theoretical Domains Framework
    (2022-06-03) Pike, Andrea; Patey, Andrea; Lawrence, Rebecca; Aubrey-Bassler, Kris; Grimshaw, Jeremy; Mortazhejri, Sameh; Dowling, Shawn; Jasaui, Yamile; Hall, Amanda
    Abstract Background Low back pain (LBP) is a leading cause of disability and is among the top five reasons that patients visit their family doctors. Over-imaging for non-specific low back pain remains a problem in primary care. To inform a larger study to develop and evaluate a theory-based intervention to reduce inappropriate imaging, we completed an assessment of the barriers and facilitators to reducing unnecessary imaging for NSLBP among family doctors in Newfoundland and Labrador (NL). Methods This was an exploratory, qualitative study describing family doctors’ experiences and practices related to diagnostic imaging for non-specific LBP in NL, guided by the Theoretical Domains Framework (TDF). Data were collected using in-depth, semi-structured interviews. Transcripts were analyzed deductively (assigning text to one or more domains) and inductively (generating themes at each of the domains) before the results were examined to determine which domains should be targeted to reduce imaging. Results Nine family doctors (four males; five females) working in community (n = 4) and academic (n = 5) clinics in both rural (n = 6) and urban (n = 3) settings participated in this study. We found five barriers to reducing imaging for patients with NSLBP: 1) negative consequences, 2) patient demand 3) health system organization, 4) time, and 5) access to resources. These were related to the following domains: 1) beliefs about consequences, 2) beliefs about capabilities, 3) emotion, 4) reinforcement, 5) environmental context and resources, 6) social influences, and 7) behavioural regulation. Conclusions Family physicians a) fear that if they do not image they may miss something serious, b) face significant patient demand for imaging, c) are working in a system that encourages unnecessary imaging, d) don’t have enough time to counsel patients about why they don’t need imaging, and e) lack access to appropriate practitioners, community programs, and treatment modalities to prescribe to their patients. These barriers were related to seven TDF domains. Successfully reducing inappropriate imaging requires a comprehensive intervention that addresses these barriers using established behaviour change techniques. These techniques should be matched directly to relevant TDF domains. The results of our study represent the important first step of this process – identifying the contextual barriers and the domains to which they are related.
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    Beyond guideline knowledge: a theory-based qualitative study of low-value preoperative testing
    (2023-03-02) Jasaui, Yamile; Mortazhejri, Sameh; Dowling, Shawn; Duquette, D’Arcy; L’Heureux, Geralyn; Linklater, Stefanie; Mrklas, Kelly J.; Wilkinson, Gloria; Beesoon, Sanjay; Patey, Andrea M.; Ruzycki, Shannon M.; Grimshaw, Jeremy M.
    Abstract Background Choosing Wisely Canada and most major anesthesia and preoperative guidelines recommend against obtaining preoperative tests before low-risk procedures. However, these recommendations alone have not reduced low-value test ordering. In this study, the theoretical domains framework (TDF) was used to understand the drivers of preoperative electrocardiogram (ECG) and chest X-ray (CXR) ordering for patients undergoing low-risk surgery (‘low-value preoperative testing’) among anesthesiologists, internal medicine specialists, nurses, and surgeons. Methods Using snowball sampling, preoperative clinicians working in a single health system in Canada were recruited for semi-structured interviews about low-value preoperative testing. The interview guide was developed using the TDF to identify the factors that influence preoperative ECG and CXR ordering. Interview content was deductively coded using TDF domains and specific beliefs were identified by grouping similar utterances. Domain relevance was established based on belief statement frequency, presence of conflicting beliefs, and perceived influence over preoperative test ordering practices. Results Sixteen clinicians (7 anesthesiologists, 4 internists, 1 nurse, and 4 surgeons) participated. Eight of the 12 TDF domains were identified as the drivers of preoperative test ordering. While most participants agreed that the guidelines were helpful, they also expressed distrust in the evidence behind them (knowledge). Both a lack of clarity about the responsibilities of the specialties involved in the preoperative process and the ease by which any clinician could order, but not cancel tests, were drivers of low-value preoperative test ordering (social/professional role and identity, social influences, belief about capabilities). Additionally, low-value tests could also be ordered by nurses or the surgeon and may be completed before the anesthesia or internal medicine preoperative assessment appointment (environmental context and resources, beliefs about capabilities). Finally, while participants agreed that they did not intend to routinely order low-value tests and understood that these would not benefit patient outcomes, they also reported ordering tests to prevent surgery cancellations and problems during surgery (motivation and goals, beliefs about consequences, social influences). Conclusions We identified key factors that anesthesiologists, internists, nurses, and surgeons believe influence preoperative test ordering for patients undergoing low-risk surgeries. These beliefs highlight the need to shift away from knowledge-based interventions and focus instead on understanding local drivers of behaviour and target change at the individual, team, and institutional levels.
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    Effects of Repetitive Transcranial Magnetic Stimulation and Possible Predictors of Response in Youth with Treatment Resistant Depression
    (2016) Jasaui, Yamile; MacMaster, Frank; Hill, Matthew; Patten, Scott
    Adolescents with treatment-resistant depression (TRD) do not respond to conventional antidepressant interventions. Repetitive transcranial magnetic stimulation (rTMS) is a novel therapeutic technique to treat TRD. The left dorsolateral prefrontal cortex (DLPFC), important in emotion regulation and the excitatory neurotransmitter glutamate, are altered in TRD. rTMS applied to the left DLPFC can increase glutamate concentrations in this area. Adolescents (aged 12-21) underwent 3 weeks of rTMS, pre and post magnetic resonance spectroscopy (MRS) to measure glutamate concentrations and weekly Ham-D depression rating scale applications. A 50% reduction in depression scores indicated response to treatment. Depression scores decreased in all participants but declined significantly in responders whose glutamate concentrations pre-treatment were considerably lower. Thus, low glutamate concentrations pre-treatment might be a biomarker of response to rTMS. One explanation for this result is that rTMS stimulates glutamate release, which activates the left DLPFC’s emotional regulation function, which in turn reduces depressive symptomatology.