Browsing by Author "Mardinger, Cynthia"

Now showing 1 - 2 of 2
  • Thumbnail Image
    ItemOpen Access
    National Surgical Quality Improvement Program: A Scoping Review of the Literature and Real-World Application Among Radical Cystectomy Patients
    (2022-05-09) Mardinger, Cynthia; Kortbeek, John; Hyndman, Eric; Brindle, Mary; Yergens, Dean; Hee Lee, Chel; Fraulin, Frankie; Austen, Lea
    Introduction: The National Surgical Quality Improvement Program (NSQIP) is a validated database designed to measure risk-adjusted 30-day surgical outcomes for national and international benchmarking. De-identified, anonymized datasets can be abstracted from submitting NSQIP hospitals. The purpose of this scoping review is to describe the breadth of studies in the NSQIP literature. Methods: A comprehensive electronic literature search was performed using PubMed, MEDLINE, Web of Knowledge and Scopus to capture all NSQIP articles published between January 1, 2000 and December 31, 2020. Two reviewers independently reviewed articles to determine their relevance using predefined inclusion criteria. Articles were included if they were about NSQIP or used NSQIP data. References were imported into a literature review application, Synthesis®, to semi-automate data management. Extracted data included the domain of surgery, study type, and year of publication. Results: Of the 4,661 NSQIP articles included, 77.9% were published within the last 5 years. Outcomes (46.7%) and Association (41.7%) were the most common types of NSQIP-related articles. The most common surgical domains of NSQIP articles were general surgery and orthopedic surgery, representing 35.7% and 24.0% of the articles, respectively. Overall, 52 (1.1%) articles could not be categorized. Conclusion: This scoping review provides an overview of the diversity of articles in the NSQIP literature. Mapping the NSQIP database identified areas where systematic reviews might be feasible or relevant and identified opportunities for future research.
  • Thumbnail Image
    ItemOpen Access
    Thrombolysis of Postoperative Acute Pulmonary Embolism with a Thrombus in Transit
    (2020-05-20) Mardinger, Cynthia; Boiteau, Paul J. E.; Kortbeek, John B.
    Right heart thrombus in transit clot (RHTT) associated with a pulmonary thromboembolism (PTE) is a rare but potentially fatal diagnosis. Early diagnosis and immediate intervention are crucial. This report describes the case of a healthy, physically active 32-year-old female who presented 19 days postoperatively, following an anterior cruciate ligament reconstruction and partial lateral meniscectomy with a saddle PE, RHTT, and right ventricular (RV) strain. The patient received half of the standard dose of intravenous tissue plasminogen activator (TPA) in combination with anticoagulation and survived. Case reports of RHTT will inform future studies designed to evaluate whether and when thrombolysis should be administered.