Browsing by Author "Tai, Davina Julia"

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    Pneumatic compression devices during hemodialysis
    (2012-08-28) Tai, Davina Julia; Ahmed, Sofia B.; MacRae, Jennifer M.
    Hemodynamic stability during hemodialysis requires maintenance of central blood volume (CBV), which pneumatic compression devices (PCDs) may help preserve. We performed a randomized crossover trial to determine the effect of PCDs on CBV during hemodialysis. Fifty-one patients were randomized to begin the first of two hemodialysis sessions with or without PCDs. The median change in CBV for PCDs vs control was -0.08 vs -0.05L (p=0.62). There was no difference in change in cardiac output (-0.63 vs -0.49L/min, p=0.78) or systemic vascular resistance (+1.30 vs +1.55mmHg/L/min, p=0.67) for PCDs vs control. There was a greater reduction in total body water (-2.6 vs -2.3L, p=0.05) and intracellular fluid volume (-1.3 vs -1.1L, p=0.03), with no difference in extracellular fluid volume (-1.3 vs -1.2L, p=0.09) for PCDs vs control. Compared with standard of care, PCDs have no effect on intradialytic hemodynamic parameters, including CBV, although they may allow greater capacity for fluid removal.