Clinical manifestations and diagnostic methods in pulmonary angiosarcoma: protocol for a scoping review

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dc.contributor.authorLim, Rachel
dc.contributor.authorHarper, Lea
dc.contributor.authorSwiston, John
dc.date.accessioned2018-11-07T17:05:21Z
dc.date.available2018-11-07T17:05:21Z
dc.date.issued2017-07-10
dc.date.updated2018-11-07T17:05:21Z
dc.description.abstractAbstract Background Angiosarcoma involving the lung can represent either primary or metastatic malignancy. Due to the rarity of this condition, knowledge surrounding the natural history and clinical presentation is scarce. The aim of this scoping review is to summarize the existing literature on pulmonary angiosarcoma, particularly as it pertains to the clinical presentation and ancillary tests used for diagnosis in addition to histopathology. Methods We will conduct a systematic search using Ovid MEDLINE and EMBASE electronic databases. Two investigators will independently screen identified titles and abstracts to select articles reporting on pulmonary angiosarcoma. The data will be summarized in a narrative fashion and organized according to aspects of epidemiology, risk factors, clinical presentation, diagnostic methods, and treatment. Discussion Scoping reviews are increasingly used to synthesize the evidence on a particular topic, to identify gaps in the literature, and to determine if future systematic reviews are feasible. In order to improve the care of patients with angiosarcoma, earlier recognition and diagnosis is required. This review will be valuable for highlighting the range of clinical presentations and the role of imaging and other diagnostic tools in the diagnosis of metastatic and primary pulmonary angiosarcoma. Systematic review registration PROSPERO registration: CRD42017059052
dc.identifier.citationSystematic Reviews. 2017 Jul 10;6(1):136
dc.identifier.doihttps://doi.org/10.1186/s13643-017-0531-6
dc.identifier.urihttp://hdl.handle.net/1880/109056
dc.identifier.urihttps://doi.org/10.11575/PRISM/44006
dc.language.rfc3066en
dc.rights.holderThe Author(s).
dc.titleClinical manifestations and diagnostic methods in pulmonary angiosarcoma: protocol for a scoping review
dc.typeJournal Article
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