Immune Response in Young Men to the 2014/15 Seasonal Influenza Vaccine

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atmire.migration.oldid4150
dc.contributor.advisorDoyle-Baker, Patricia Katherine
dc.contributor.authorStewart, Andrew
dc.contributor.committeememberReimer, Raylene
dc.contributor.committeememberVanderkooi, Otto
dc.date.accessioned2016-02-04T20:22:26Z
dc.date.available2016-02-04T20:22:26Z
dc.date.issued2016-02-04
dc.date.submitted2016en
dc.description.abstractCurrently there is limited research on the impact of adiposity and physical activity on influenza vaccination. The purpose of this pilot study was to investigate the role of adiposity and physical activity in the immune response of males aged 18-35 to the 2014/2015 seasonal trivalent influenza vaccine. Blood was drawn pre and four weeks post vaccination. Serum samples were analyzed for changes in antibody titers, serum leptin, soluble leptin receptors (sLEPR) and C-reactive protein (CRP). No differences in median percent body fat, leptin, sLEPR or CRP were associated with seroconversion rates. Participants with higher physical activity scores had lower seroconversion rates. Differences were found for the A/Texas strain (p<0.01) with a similar trend observed for the other influenza strains. Further work needs to be done in this area to confirm this trend.en_US
dc.identifier.citationStewart, A. (2016). Immune Response in Young Men to the 2014/15 Seasonal Influenza Vaccine (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/26453en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/26453
dc.identifier.urihttp://hdl.handle.net/11023/2837
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.facultyKinesiology
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectEducation--Health
dc.subjectEducation--Physical
dc.subjectVirology
dc.subjectImmunology
dc.subject.classificationKinesiologyen_US
dc.subject.classificationPhysical Activityen_US
dc.subject.classificationInfluenzaen_US
dc.subject.classificationVaccineen_US
dc.subject.classificationMenen_US
dc.subject.classificationBody Compositionen_US
dc.subject.classificationImmune Responseen_US
dc.titleImmune Response in Young Men to the 2014/15 Seasonal Influenza Vaccine
dc.typemaster thesis
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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