Capsule endoscopy versus standard of care in obscure gastrointestinal bleeding: A randomized controlled trial

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atmire.migration.oldid6083
dc.contributor.advisorHilsden, Robert J
dc.contributor.authorAdams, Fatin
dc.contributor.committeememberDube, Jeanne Catherine
dc.contributor.committeememberKaplan, Gil
dc.contributor.committeememberMcGregor, Elizabeth SE
dc.date.accessioned2017-09-28T22:47:08Z
dc.date.available2017-09-28T22:47:08Z
dc.date.issued2017
dc.date.submitted2017en
dc.description.abstractIron deficiency anemia (IDA) is a common problem worldwide. The initial workup usually involves performing a bidirectional endoscopy. When negative, the small bowel could be the source of obscure gastrointestinal bleeding presenting as IDA. The next best diagnostic test is uncertain. Wireless capsule endoscopy (WCE) is a non-invasive new technology that allows examination of the entire small bowel. Methods: We designed a randomized controlled pilot study to outline the challenges for conducting a full randomized controlled trial (RCT) to determine if WCE should be first-line investigation in such cases. 109 patients were enrolled; 55 intervention (WCE) & 54 controls (standard of care) (SC). Results: Two-years post-randomization there was no difference in anemia between the two groups. Conclusion: Few methodological hurdles for conducting a full RCT were identified.en_US
dc.identifier.citationAdams, F. (2017). Capsule endoscopy versus standard of care in obscure gastrointestinal bleeding: A randomized controlled trial (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/25206en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/25206
dc.identifier.urihttp://hdl.handle.net/11023/4162
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectEpidemiology
dc.subject.otherIron deficiency anemia
dc.subject.otherobscure occult gastrointestinal bleeding
dc.subject.othercapsule endoscopy
dc.titleCapsule endoscopy versus standard of care in obscure gastrointestinal bleeding: A randomized controlled trial
dc.typemaster thesis
thesis.degree.disciplineCommunity Health Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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