Design and Synthesis of a New Family of Amphiphilic beta-Cyclodextrin  Liquid Crystals.

Trudel Lachance, Simon

Design and Synthesis of a New Family of Amphiphilic beta-Cyclodextrin Liquid Crystals.

dc.contributor.advisor	Ling, Changchun
dc.contributor.author	Trudel Lachance, Simon
dc.contributor.committeemember	MacCallum, Justin L.
dc.contributor.committeemember	Derksen, Darren J.
dc.date	2020-11
dc.date.accessioned	2020-07-07T16:00:53Z
dc.date.available	2020-07-07T16:00:53Z
dc.date.issued	2020-06-30
dc.description.abstract	The field of liquid crystals has fascinated scientists since 1888 when a molecule of cholesteryl benzoate exhibited two different melting points. It corresponds to a state of matter between the isotropic liquid and the crystalline solid-state. Since then, the field has grown, and liquid crystal-based materials have become an important component of our lives. Cyclodextrin (CD) are polyhydroxylated macrocycles containing 6-8 units of beta-D-glucopyranose units linked together via a series of alpha-1,4-glycosidic linkages. The formed macrocycles are shaped like a truncated cone that combines two hydrophilic surfaces and a hydrophobic cavity that can be used to form inclusion complexes with different organic molecules. Our group has been developing chemistries to modify the two hydrophilic surfaces of CDs by a variety of chemical methodologies to generate amphiphilic molecules capable of self-assembling into liquid crystalline mesophases. This thesis focuses on the synthesis a new family of amphiphilic CDs for liquid crystal research. These CD-derivatives can be easily obtained via polyesterification at one of the hydrophilic faces with hydrophobic aliphatic chains and installation of functionalized oligoethylene glycols at the other surface via the copper(I)-catalyzed Huigsen 1,3-dipolar cycloaddition. These novel amphiphilic CD derivatives have been characterized by polarized optical microscopy, thermogravimetric analysis and differential scanning calorimetry.	en_US
dc.identifier.citation	Trudel Lachance, S. (2020). Design and Synthesis of a New Family of Amphiphilic beta-Cyclodextrin Liquid Crystals. (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca.	en_US
dc.identifier.doi	http://dx.doi.org/10.11575/PRISM/37981
dc.identifier.uri	http://hdl.handle.net/1880/112259
dc.language.iso	eng	en_US
dc.language.iso	fre	en_US
dc.publisher.faculty	Science	en_US
dc.publisher.institution	University of Calgary	en
dc.rights	University of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.	en_US
dc.subject	Liquid Crystal, Cyclodextrin, Chemistry.	en_US
dc.subject.classification	Engineering--Chemical	en_US
dc.title	Design and Synthesis of a New Family of Amphiphilic beta-Cyclodextrin Liquid Crystals.	en_US
dc.type	master thesis	en_US
thesis.degree.discipline	Chemistry	en_US
thesis.degree.grantor	University of Calgary	en_US
thesis.degree.name	Master of Science (MSc)	en_US
ucalgary.item.requestcopy	true	en_US