The influence of maximal and submaximal cyclic concentric and eccentric exercise on chondrocyte death and synovial fluid proteins in the rabbit knee
Date
2020-08
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Mechanical stimulation of joints regulates the biosynthetic activity of chondrocytes. It has been argued that excessive loading might cause chondrocyte death, leading to degeneration of cartilage and cause osteoarthritis. The aims of this study were to apply a high, short-term loading, and a low intensity, long-term loading protocol to intact joints in life animals and determine changes in synovial fluid and the percentage of dead cells in rabbit knee cartilage
Description
Keywords
Muscular loading, Synovial fluid, Protein content, Chondrocytes, Cell viability
Citation
Abughazaleh, N., Abusara, Z., Krawetz, R., & Herzog, W. (2020). The influence of maximal and submaximal cyclic concentric and eccentric exercise on chondrocyte death and synovial fluid proteins in the rabbit knee. Clinical Biomechanics, 78 doi:10.1016/j.clinbiomech.2020.105095