Measuring Observer Agreement on Categorical Data

atmire.migration.oldid3075
dc.contributor.advisorEliasziw, Misha
dc.contributor.advisorFick, Gordon
dc.contributor.authorSoo, Andrea
dc.date.accessioned2015-04-23T22:13:33Z
dc.date.available2015-06-22T07:00:46Z
dc.date.issued2015-04-23
dc.date.submitted2015en
dc.description.abstractIn order for a patient to receive proper and appropriate health care, one requires error-free assessment of clinical measurements. For example, a diagnostic test that assesses whether an individual will be classified as having the disease or not having the disease needs to produce accurate and reliable results in order to ensure that an individual who needs treatment receives the correct therapy. Agreement and reliability studies aim to evaluate the accuracy and consistency of diagnostic tests or measurement tools. A model developed by Shoukri and Donner allows for the concurrent assessment of inter-rater (between rater) agreement and intra-rater (within rater) reliability, by incorporating two measurements per rater per subject. The main purpose of this research was to develop methods for the maximum likelihood (ML) approach using the Shoukri-Donner model and compare those methods to the method of moments (MM) approach using Monte Carlo computer simulation studies. Little differences between ML and MM were observed in point estimation. In general, the MM Wald test and MM confidence interval (CI) performed better than any of the other methods. In fact, the goodness of fit (GOF) test and GOF CI (for both ML and MM) were shown to have high empirical type I errors and low coverage levels, respectively, for the inter-rater agreement parameter in some parameter combinations for the 3 parameter case and all considered parameter combinations in the 4 parameter case. Further investigation as to why there is poor performance with the GOF approach needs to be done before one could recommend this approach as a better alternative to the MM approach. Also, it does not appear that the ML approach is necessarily better than the MM approach. Lastly, extending this research to a more general 5 parameter model requires the resolution of several issues before it can be evaluated in point estimation, hypothesis testing, and CI construction.en_US
dc.identifier.citationSoo, A. (2015). Measuring Observer Agreement on Categorical Data (Doctoral thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/26858en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/26858
dc.identifier.urihttp://hdl.handle.net/11023/2158
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectBiostatistics
dc.subjectStatistics
dc.subject.classificationAgreementen_US
dc.subject.classificationReliabilityen_US
dc.subject.classificationKappaen_US
dc.titleMeasuring Observer Agreement on Categorical Data
dc.typedoctoral thesis
thesis.degree.disciplineCommunity Health Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameDoctor of Philosophy (PhD)
ucalgary.item.requestcopytrue
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