Adverse Effects of Remediated and Unremediated Oil Sands Process-Affected Water on Zebrafish Embryo Morphological Development

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atmire.migration.oldid4745
dc.contributor.advisorHabibi, Hamid
dc.contributor.advisorChua, Gordon
dc.contributor.authorToth, Cameron Graham Andrew
dc.contributor.committeememberGieg, Lisa
dc.contributor.committeememberSmits, Judit
dc.date.accessioned2016-08-22T19:25:53Z
dc.date.available2016-08-22T19:25:53Z
dc.date.issued2016
dc.date.submitted2016en
dc.description.abstractOil sands process-affected water (OSPW) generated from bitumen extraction in the Alberta oil sands is accumulating in on-site tailings ponds. The organic fraction of OSPW is a primary target for remediation as it is toxic to aquatic organisms. Here, robust morphometric biomarkers were identified in developing zebrafish (Danio rerio) embryos for determining the acute toxicities of the acid extracted organics (AEOs) and diluted OSPW. AEOs/OSPW exposures reduced survival and increased cardiovascular, growth, swim bladder and behavioural abnormalities in zebrafish embryos. Phosphate biostimulation of indigenous algal species in OSPW reduced the C5 – C12 cluster of naphthenic acids (NAs) abundance in the AEO fraction by ≥ 50%. Following phosphate biostimulation, embryonic zebrafish endpoints previously sensitive to AEO/OSPW constituents were ameliorated. These findings implicate the acute toxicity of C5 – C12 NAs on zebrafish development and highlight the potential of algal-based NA biodegradation for reducing the impact of OSPW to aquatic organisms.en_US
dc.identifier.citationToth, C. G. (2016). Adverse Effects of Remediated and Unremediated Oil Sands Process-Affected Water on Zebrafish Embryo Morphological Development (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/24730en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/24730
dc.identifier.urihttp://hdl.handle.net/11023/3198
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectAnimal Physiology
dc.subjectPhysiology
dc.subjectToxicology
dc.subject.classificationzebrafishen_US
dc.subject.classificationOSPWen_US
dc.subject.classificationAEOen_US
dc.subject.classificationNAsen_US
dc.subject.classificationBiotsimulationen_US
dc.subject.classificationToxicityen_US
dc.subject.classificationBiomarkersen_US
dc.titleAdverse Effects of Remediated and Unremediated Oil Sands Process-Affected Water on Zebrafish Embryo Morphological Development
dc.typemaster thesis
thesis.degree.disciplineBiological Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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