Noninvasive Ventilation Practice Patterns for Acute Respiratory Failure in Canadian Tertiary Care Centres: A Descriptive Analysis

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dc.contributor.authorDigby, Geneviève C
dc.contributor.authorKeenan, Sean P
dc.contributor.authorParker, Christopher M
dc.contributor.authorSinuff, Tasnim
dc.contributor.authorBurns, Karen E
dc.contributor.authorMehta, Sangeeta
dc.contributor.authorRonco, Juan J
dc.contributor.authorKutsogiannis, Demetrios J
dc.contributor.authorRose, Louise
dc.contributor.authorAyas, Najib T
dc.contributor.authorBerthiaume, Luc R
dc.contributor.authorD’Arsigny, Christine L
dc.contributor.authorStollery, Daniel E
dc.contributor.authorMuscedere, John
dc.date.accessioned2018-09-27T11:29:04Z
dc.date.available2018-09-27T11:29:04Z
dc.date.issued2015-01-01
dc.date.updated2018-09-27T11:29:03Z
dc.description.abstractBACKGROUND: The extent of noninvasive ventilation (NIV) use for patients with acute respiratory failure in Canadian hospitals, indications for use and associated outcomes are unknown.OBJECTIVE: To describe NIV practice variation in the acute setting.METHODS: A prospective observational study involving 11 Canadian tertiary care centres was performed. Data regarding NIV indication, mode and outcomes were collected for all adults (>16 years of age) treated with NIV for acute respiratory failure during a four-week period (between February and August 2011). Logistic regression with site as a random effect was used to examine the association between preselected predictors and mortality or intubation.RESULTS: A total of 330 patients (mean [± SD] 30±12 per centre) were included. The most common indications for NIV initiation were pulmonary edema (104 [31.5%]) and chronic obstructive pulmonary disease (99 [30.0%]). Significant differences in indications for NIV use across sites, specialty of ordering physician and location of NIV initiation were noted. Although intubation rates were not statistically different among sites (range 10.3% to 45.4%), mortality varied significantly (range 6.7% to 54.5%; P=0.006). In multivariate analysis, the most significant independent predictor of avoiding intubation was do-not-resuscitate status (OR 0.11 [95% CI 0.03 to 0.37]).CONCLUSION: Significant variability existed in NIV use and associated outcomes among Canadian tertiary care centres. Assignment of do-not-resuscitate status prevented intubation.
dc.description.versionPeer Reviewed
dc.identifier.citationGeneviève C Digby, Sean P Keenan, Christopher M Parker, et al., “Noninvasive Ventilation Practice Patterns for Acute Respiratory Failure in Canadian Tertiary Care Centres: A Descriptive Analysis,” Canadian Respiratory Journal, vol. 22, no. 6, pp. 331-340, 2015. doi:10.1155/2015/971218
dc.identifier.doihttps://doi.org/10.1155/2015/971218
dc.identifier.urihttp://hdl.handle.net/1880/108163
dc.identifier.urihttps://doi.org/10.11575/PRISM/45043
dc.language.rfc3066en
dc.rights.holderCopyright © 2015 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleNoninvasive Ventilation Practice Patterns for Acute Respiratory Failure in Canadian Tertiary Care Centres: A Descriptive Analysis
dc.typeJournal Article
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