Large Scale Elasto-plastic Modelling for in vivo Assessment of Bone Strength from High Resolution Peripheral Quantitative Computed Tomography

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atmire.migration.oldid1214
dc.contributor.advisorBoyd, Steven Kyle
dc.contributor.authorOwoc, Jan Stanislaw
dc.date.accessioned2013-08-09T20:25:55Z
dc.date.available2013-11-12T08:00:10Z
dc.date.issued2013-08-09
dc.date.submitted2013en
dc.description.abstractOsteoporosis is a "silent epidemic" of weakening bones, often leading to fracture. To predict fracture, the finite element method based on micro-computed tomography can be used, modelling bone behaviour under load. Elasto-plastic finite element modelling is able to directly calculate bone strength, but until recently it has been computationally expensive. Advancements in GPU technology have exponentially increased the computational power available in consumer-grade hardware and enabled the implementation of a custom elasto-plastic finite element solver for large-scale models. Both analytical and mechanical validation of the elasto-plastic solver was performed. Elasto-plastic finite element models based on tomography data were able to predict failure load with a correlation coefficient of 0.81. These new developments in elasto-plastic finite element modelling have enabled the direct estimation of patient-specific yield properties on consumer-grade hardware.en_US
dc.identifier.citationOwoc, J. S. (2013). Large Scale Elasto-plastic Modelling for in vivo Assessment of Bone Strength from High Resolution Peripheral Quantitative Computed Tomography (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/26726en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/26726
dc.identifier.urihttp://hdl.handle.net/11023/870
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectComputer Science
dc.subjectBiomedical
dc.subjectMechanical
dc.subject.classificationbone fractureen_US
dc.subject.classificationFinite Element Analysisen_US
dc.subject.classificationelasto-plasticen_US
dc.subject.classificationosteoporosisen_US
dc.titleLarge Scale Elasto-plastic Modelling for in vivo Assessment of Bone Strength from High Resolution Peripheral Quantitative Computed Tomography
dc.typemaster thesis
thesis.degree.disciplineBiomedical Engineering
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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