Relaxin's Potential Implications in Early Pregnancy in Mares
Abstract
Relaxin is expressed at high levels from the conceptus during the first 16 d of pregnancy in mares. The overall objective was to determine the potential implications of relaxin in equine endometrium, and the expression of RLN, RXFP1, RXFP2, RXFP3 and RXFP4 in pregnant and non-pregnant equine endometrium as well as in the conceptus. The location of RXFP1 in pregnant endometrium was examined and effects of relaxin on inhibition of PGF2α were detailed. The hypothesis that relaxin inhibits endometrial release of PGF2α and is the maternal recognition of pregnancy factor in mares was tested. This hypothesis was rejected with the conclusion that whereas relaxin is important in equine pregnancy, it is not the maternal recognition of pregnancy factor.
Description
Keywords
Veterinary Science
Citation
Schwinghamer, R. A. (2016). Relaxin's Potential Implications in Early Pregnancy in Mares (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/27611