Blood Volume Monitoring Guided Ultrafiltration Biofeedback on the Reduction of Intradialytic Hypotensive Episodes in Hemodialysis
Abstract
The majority of patients with end stage renal disease rely on hemodialysis (HD) to maintain fluid balance. Unfortunately, rapid fluid removal [ultrafiltration (UF)] often results in symptomatic, intradialytic hypotension (IDH). Our objective was to perform a randomized controlled crossover trial to evaluate the effectiveness of a blood volume monitoring guided UF biofeedback in the reduction of symptomatic IDH. Over the study period, symptomatic patients first had their dialysis prescription and dry weight optimized over a four-week period before being randomized to an eight-week biofeedback intervention or standard control HD. There was a two-week washout period before patients crossed over for a second eight-week study period. There were no differences in the rate of symptomatic IDH, volume status (as measured by electrical bioimpedance), or biomarkers of cardiac stress between the two groups.
Description
Keywords
Medicine and Surgery
Citation
Leung, K. C. (2016). Blood Volume Monitoring Guided Ultrafiltration Biofeedback on the Reduction of Intradialytic Hypotensive Episodes in Hemodialysis (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/25151