Effects of Acute and Chronic Hypoxia Exposure on the Contractile Properties of Isolated Compact and Spongy Ventricular Myocardium From Rainbow Trout (Oncorhynchus mykiss)

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atmire.migration.oldid4530
dc.contributor.advisorSyme, Douglas
dc.contributor.authorRoberts, Jordan Cyril
dc.contributor.committeememberVijayan, Matt
dc.contributor.committeememberRogers, Sean
dc.contributor.committeememberTyberg, John
dc.date.accessioned2016-06-24T18:15:34Z
dc.date.available2016-06-24T18:15:34Z
dc.date.issued2016
dc.date.submitted2016en
dc.description.abstractThe ventricle of salmonids is composed of an outer compact layer, routinely supplied with well-oxygenated arterial blood, and inner spongy myocardium receiving low oxygen venous blood. During hypoxia oxygen exposures for both these tissue layers declines. As well, hypoxia results in an increase to circulating epinephrine for trout, which may affect the contractile response during hypoxia. This thesis presents an investigation into effects of high epinephrine, as well, acute and chronic hypoxia exposure on the contractile performance of these ventricular tissues from rainbow trout (Oncorhynchus mykiss). Acute hypoxia resulted in a similar decline to work output in compact and spongy myocardium. High epinephrine however, improved contractile performance of spongy myocardium during hypoxia. Hypoxia acclimation resulted in a decline to work output from spongy myocardium across all oxygen exposures. It appears hypoxia causes a decline in ventricular performance; however, elevated epinephrine exposure may be important to maintain higher performance during hypoxia.en_US
dc.identifier.citationRoberts, J. C. (2016). Effects of Acute and Chronic Hypoxia Exposure on the Contractile Properties of Isolated Compact and Spongy Ventricular Myocardium From Rainbow Trout (Oncorhynchus mykiss) (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/25815en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/25815
dc.identifier.urihttp://hdl.handle.net/11023/3080
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectAnimal Physiology
dc.subjectPhysiology
dc.subjectZoology
dc.subject.classificationRainbow trouten_US
dc.subject.classificationhypoxiaen_US
dc.subject.classificationCardiac functionen_US
dc.subject.classificationMyocardiumen_US
dc.subject.classificationEnvironmental Stressen_US
dc.titleEffects of Acute and Chronic Hypoxia Exposure on the Contractile Properties of Isolated Compact and Spongy Ventricular Myocardium From Rainbow Trout (Oncorhynchus mykiss)
dc.typemaster thesis
thesis.degree.disciplineBiological Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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