The Relationship Between Cardiac Scar and Electrical Markers of Sudden Cardiac Arrest Risk

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dc.contributor.advisorExner, Derek Vincent
dc.contributor.authorVaid, Haris Munir
dc.date.accessioned2015-10-05T16:25:08Z
dc.date.embargolift2017-10-04T16:25:08Z
dc.date.issued2015-10-05
dc.date.submitted2015en
dc.description.abstractThe optimal approach to identifying patients at risk of serious arrhythmias after myocardial infarction (MI) is unclear. Electrocardiographic markers, including T-wave alternans (TWA) and Heart Rate Turbulence (HRT) and myocardial scar characteristics, assessed via cardiac magnetic resonance (CMR), appear to provide useful information in this regard. However, the relationship between electrical and structural markers is unclear. A meta-analysis was conducted and demonstrated the utility of HRT after MI. In addition, a cross-sectional study was performed to assess the relationships of HRT and TWA with CMR-assessed myocardial scar extent and pattern. A total of 99 patients were enrolled 3-15 months after MI. No linear relationship between TWA and scar was observed. Yet, maximal TWA values were higher in patients with transmural versus non-trans-mural scar; particularly those with anterior, trans-mural scar. HRT slope was not related to myocardial scar. Based on these data, additional research is recommended to better define these relationships.en_US
dc.description.embargoterms2 yearsen_US
dc.identifier.citationVaid, H. M. (2015). The Relationship Between Cardiac Scar and Electrical Markers of Sudden Cardiac Arrest Risk (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/28296en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/28296
dc.identifier.urihttp://hdl.handle.net/11023/2604
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectMedicine and Surgery
dc.subject.classificationSudden Cardiac Deathen_US
dc.subject.classificationElectrophysiologyen_US
dc.subject.classificationCardiac Magnetic Resonance Imagingen_US
dc.subject.classificationT-Wave Alternansen_US
dc.subject.classificationHeart Rate Turbulenceen_US
dc.subject.classificationCardiac Scaren_US
dc.subject.classificationRisk Stratificationen_US
dc.subject.classificationmyocardial infarctionen_US
dc.titleThe Relationship Between Cardiac Scar and Electrical Markers of Sudden Cardiac Arrest Risk
dc.typemaster thesis
thesis.degree.disciplineCardiovascular & Respiratory Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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