Characterizing the effect of precise exercise intensity prescription on physiological adaptations to endurance training - an intensity domain-specific approach

dc.contributor.advisorMurias, Juan M
dc.contributor.advisorReimer De Bruyn, Raylene A
dc.contributor.authorInglis, Erin Calaine
dc.contributor.committeememberKeir, Daniel A
dc.contributor.committeememberAboodarda, Saied Jalal
dc.contributor.committeememberBoone, Jan
dc.contributor.committeememberTownsend, Nathan E
dc.date2023-11
dc.date.accessioned2023-06-22T16:04:50Z
dc.date.available2023-06-22T16:04:50Z
dc.date.issued2023-06
dc.description.abstractExercise intensity determines the magnitude of the metabolic disturbance which is directly related to the upregulation of signalling pathways responsible for the adaptative responses to exercise training. The exercise intensity domain schema describes four distinct domains (i.e., moderate-, heavy-, severe- and extreme-intensity) each characterized by distinct metabolic responses. These domains are separated by exercise thresholds – of which the position varies widely between individuals. The most commonly used endurance exercise intensity prescription approach utilizes a percentage of maximal values (i.e., maximal oxygen uptake (V̇O2max) or maximal heart rate (HRmax)) to assign intensity. However, a major limitation to this approach is that it ignores the existence of individual exercise thresholds and the exercise intensity domains they create. This is problematic as research has shown that a given percentage of maximal values does not ensure a homogenous metabolic disturbance across individuals which complicates the interpretation of previous research studies that utilized this approach. Therefore, the true contribution of exercise intensity in modulating changes in response to endurance exercise training is unknown. The aim of this thesis was to apply a domain-based approach that precisely accounts for the metabolic disturbance of the intervention, to allow for the determination of the true effect of intensity on V̇O2max, submaximal thresholds, oxygen uptake (V̇O2) kinetics, and central and peripheral adaptations. The main findings were that i) changes in V̇O2max were intensity-domain dependent such that, with the exception of sprint interval training (SIT), greater magnitudes of change were found with progressively greater intensities with severe-intensity exercise (i.e., high-intensity interval training) producing the greatest magnitude of change, ii) this intensity-domain dependency was less pronounced when evaluating changes in the estimated lactate threshold and the maximal metabolic steady state and did not apply to the extreme-intensity domain (i.e. was not evident with SIT), iii) greater intensities of exercise resulted in central adaptations (i.e., maximal cardiac output and maximal stroke volume), with evidence for some peripheral adaptations to be present as well, iv) when compared to control, there was an equal speeding of V̇O2 kinetics across intervention with no significant correlations between changes in the speed of V̇O2 kinetics and performance variables.
dc.identifier.citationInglis, E. C. (2023). Characterizing the effect of precise exercise intensity prescription on physiological adaptations to endurance training - an intensity domain-specific approach (Doctoral thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca.
dc.identifier.urihttps://hdl.handle.net/1880/116640
dc.identifier.urihttps://dx.doi.org/10.11575/PRISM/41483
dc.language.isoen
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgary
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectEndurance training
dc.subjectExercise Intensity Domains
dc.subjectVO2max
dc.subjectCentral and Peripheral Adaptations
dc.subjectVO2 kinetics
dc.subject.classificationPhysiology
dc.titleCharacterizing the effect of precise exercise intensity prescription on physiological adaptations to endurance training - an intensity domain-specific approach
dc.typedoctoral thesis
thesis.degree.disciplineKinesiology
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameDoctor of Philosophy (PhD)
ucalgary.thesis.accesssetbystudentI do not require a thesis withhold – my thesis will have open access and can be viewed and downloaded publicly as soon as possible.
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