Accuracy of motor assessment in the diagnosis of fetal alcohol spectrum disorder
| dc.contributor.author | Johnston, Danielle | |
| dc.contributor.author | Branton, Erin | |
| dc.contributor.author | Rasmuson, Leah | |
| dc.contributor.author | Schell, Sylvia | |
| dc.contributor.author | Gross, Douglas P | |
| dc.contributor.author | Pritchard-Wiart, Lesley | |
| dc.date.accessioned | 2019-06-02T00:41:55Z | |
| dc.date.available | 2019-06-02T00:41:55Z | |
| dc.date.issued | 2019-05-28 | |
| dc.date.updated | 2019-06-02T00:41:55Z | |
| dc.description.abstract | Abstract Background To evaluate the accuracy of motor assessment tools listed in Fetal alcohol spectrum disorder: a guideline for diagnosis across the lifespan (Canadian Guideline) for the purpose of fetal alcohol spectrum disorder (FASD) diagnosis. Specifically, we aimed to determine: 1) diagnostic accuracy of motor assessment tools and subtests; 2) accuracy of multiple subtests versus total scores; and 3) accuracy of alternate cut-offs. Methods Cross-sectional diagnostic study of 63 children aged 6–17 years. Diagnostic accuracy and alternate cut-offs were calculated for the Movement Assessment Battery for Children, 2nd edition (MABC-2), Bruininks-Oseretsky Test of Motor Proficiency, 2nd edition Short Form (BOT-2SF) and Beery-Buktenica Developmental Test of Visual Motor Integration, 6th edition (BeeryVMI-6). Results The MABC-2 total motor score was more sensitive (0.30; 95% CI 0.17–0.46; p < 0.01) to motor impairment in the presence of FASD than the BOT-2SF (0.02; 95% CI 0.00–0.12) at the 2nd percentile (−2SD). The MABC-2 total motor score was more accurate than any combination of subtest scores. The Motor Coordination subtest of the BeeryVMI-6 (BeeryMC) at the 5th percentile (− 1.5SD) (sensitivity 0.68, specificity 0.90) was the most accurate subtest. Conclusions The BOT-2SF was an inaccurate assessment tool for FASD diagnosis. The MABC-2 total motor score was the most accurate using current guidelines, though its sensitivity was still low. Further investigation into inclusion of single subtests and/or using a less conservative cut-off in the Canadian Guideline is warranted. | |
| dc.identifier.citation | BMC Pediatrics. 2019 May 28;19(1):171 | |
| dc.identifier.doi | https://doi.org/10.1186/s12887-019-1542-3 | |
| dc.identifier.uri | http://hdl.handle.net/1880/110459 | |
| dc.identifier.uri | https://doi.org/10.11575/PRISM/45826 | |
| dc.language.rfc3066 | en | |
| dc.rights.holder | The Author(s). | |
| dc.title | Accuracy of motor assessment in the diagnosis of fetal alcohol spectrum disorder | |
| dc.type | Journal Article |