The Prognostic Accuracy of Suggested Predictors of Failure of Medical Management for Patients with Spinal Epidural Abscess

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atmire.migration.oldid4437
dc.contributor.advisorThomas, Kenneth
dc.contributor.advisorDixon, Elijah
dc.contributor.authorStratton, Alexandra
dc.contributor.committeememberFaris, Peter
dc.contributor.committeememberTomkins-Lane, Christy
dc.date.accessioned2016-06-08T21:56:58Z
dc.date.available2016-06-08T21:56:58Z
dc.date.issued2016
dc.date.submitted2016en
dc.description.abstractControversy exists as to the first-line treatment in patients with spinal epidural abscess (SEA) who present with an intact neurologic exam—medical treatment or surgery. The aim of this thesis was to clarify treatment decision making in such patients. A systematic review and meta-analysis were first undertaken to define the risk of failure of medical treatment and to identify predictors of failure. Although the incidence of failure of medical management of SEA was found to be relatively common in published reports, estimates were highly heterogeneous between studies. Two studies were identified in the literature with prediction criteria for failure of medical management. These prediction criteria were tested in a cohort of patients from a tertiary care centre and both overestimated medical treatment failure. Once the prediction models were calibrated to our data it was Patel’s model that was superior and thus more useful for clinical decision making.en_US
dc.identifier.citationStratton, A. (2016). The Prognostic Accuracy of Suggested Predictors of Failure of Medical Management for Patients with Spinal Epidural Abscess (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/28282en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/28282
dc.identifier.urihttp://hdl.handle.net/11023/3045
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectMedicine and Surgery
dc.subject.classificationepidural abscessen_US
dc.subject.classificationspineen_US
dc.subject.classificationantibioticsen_US
dc.subject.classificationmedical managementen_US
dc.titleThe Prognostic Accuracy of Suggested Predictors of Failure of Medical Management for Patients with Spinal Epidural Abscess
dc.typemaster thesis
thesis.degree.disciplineCommunity Health Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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