Use 'em and lose 'em-activity-induced removal of calcium channels from the plasma membrane

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dc.contributor.authorVarela, Diego L.
dc.contributor.authorZamponi, Gerald W.
dc.date.accessioned2018-06-06T20:15:32Z
dc.date.available2018-06-06T20:15:32Z
dc.date.issued2007-08-16
dc.description.abstractCalcium influx via L-type (Cav1.2 and Cav1.3) calcium channels is tightly regulated to ensure optimal intracellular calcium levels. Although much is known about acute modulation of these channels by second messengers, the mechanisms that control their trafficking to and from the plasma membrane remain poorly understood. In this issue of Neuron, Green and colleagues demonstrate that the opening of L-type calcium channels results in negative feedback regulation due to their calcium-dependent internalization.en_US
dc.identifier.citationVarela, D., & Zamponi, G. W. (2007, August 16). Use ’em and Lose ’em-Activity-Induced Removal of Calcium Channels from the Plasma Membrane. Neuron. https://doi.org/10.1016/j.neuron.2007.07.033en_US
dc.identifier.doihttp://dx.doi.org/10.1016/j.neuron.2007.07.033en_US
dc.identifier.issn1097-4199
dc.identifier.urihttp://hdl.handle.net/1880/106728
dc.identifier.urihttps://doi.org/10.11575/PRISM/43860
dc.language.isoenen_US
dc.publisherElsevier Inc.en_US
dc.publisher.departmentCell Biology & Anatomyen_US
dc.publisher.departmentPhysiology & Pharmacologyen_US
dc.publisher.facultyCumming School of Medicineen_US
dc.publisher.institutionUniversity of Calgaryen_US
dc.publisher.policyhttps://www.elsevier.com/about/our-business/policiesen_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.titleUse 'em and lose 'em-activity-induced removal of calcium channels from the plasma membraneen_US
dc.typejournal articleen_US
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