Browsing by Author "Leung, Kelvin Cheuk-Wai"

Now showing 1 - 1 of 1
  • Thumbnail Image
    ItemOpen Access
    Blood Volume Monitoring Guided Ultrafiltration Biofeedback on the Reduction of Intradialytic Hypotensive Episodes in Hemodialysis
    (2016) Leung, Kelvin Cheuk-Wai; MacRae, Jennifer; Quinn, Robert; Ravani, Pietro; Duff, Henry
    The majority of patients with end stage renal disease rely on hemodialysis (HD) to maintain fluid balance. Unfortunately, rapid fluid removal [ultrafiltration (UF)] often results in symptomatic, intradialytic hypotension (IDH). Our objective was to perform a randomized controlled crossover trial to evaluate the effectiveness of a blood volume monitoring guided UF biofeedback in the reduction of symptomatic IDH. Over the study period, symptomatic patients first had their dialysis prescription and dry weight optimized over a four-week period before being randomized to an eight-week biofeedback intervention or standard control HD. There was a two-week washout period before patients crossed over for a second eight-week study period. There were no differences in the rate of symptomatic IDH, volume status (as measured by electrical bioimpedance), or biomarkers of cardiac stress between the two groups.