Molecular mechanisms of muscle force regulation: a role for titin?

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dc.contributor.authorHerzog, Walter
dc.contributor.authorDuVall, Michael M.
dc.contributor.authorLeonard, Timothy R.
dc.date.accessioned2018-09-26T17:55:49Z
dc.date.available2018-09-26T17:55:49Z
dc.date.issued2012-01
dc.description.abstractMuscle contraction and force regulation is thought to occur exclusively through the interaction of the contractile proteins actin and myosin and in accordance with the assumptions underlying the cross-bridge theory. Here, we demonstrate that a third protein, titin, plays a major role in muscle force regulation, particularly for eccentric contractions and at long muscle and sarcomere lengths.en_US
dc.identifier.citationHerzog, W., Duvall, M., & Leonard, T. R. (2012). Molecular mechanisms of muscle force regulation: a role for titin? Exercise and Sport Sciences Reviews, 40(1), 50–57.en_US
dc.identifier.doi10.1097/JES.0b013e31823cd75ben_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/34261
dc.identifier.issn1538-3008
dc.identifier.urihttp://hdl.handle.net/1880/108052
dc.language.isoenen_US
dc.publisherExercise Sport Science Reviewsen_US
dc.publisher.departmentHuman Performance Laben_US
dc.publisher.facultyKinesiologyen_US
dc.publisher.hasversionPost-printen_US
dc.publisher.institutionUniversity of Calgaryen_US
dc.publisher.policyhttp://edmgr.ovid.com/essr/accounts/ifauth.htmen_US
dc.rightsUnless otherwise indicated, this material is protected by copyright and has been made available with authorization from the copyright owner. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.subjectsarcomeresen_US
dc.subjectmyofibrilsen_US
dc.subjectcross-bridge theoryen_US
dc.subjectsliding filament theoryen_US
dc.titleMolecular mechanisms of muscle force regulation: a role for titin?en_US
dc.title.alternativeRole of titin in muscle force regulationen_US
dc.typejournal articleen_US
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